Candidate Ranking

SkillDev tools

Rank peptide variants using stability heuristics and hotspot protection; emit top candidates.

Available today. Use it from your connected AI after setup.

Connect ahel once, and every AI you use reads what you have installed.

Then ask your AI: use the Candidate Ranking skill

What this skill tells your AI

The instructions your AI receives, as published by lamm-mit/scienceclaw in skills/candidate-ranking/SKILL.md and read by ahel’s review.

Ranks candidates based on a simple weighted score:

  • stability_score (heuristic)
  • penalty for hotspot mutations if hotspot positions provided
  • penalty for edit distance vs reference sequence if provided

CLI

python3 scripts/run.py --reference AGCKNFFWKTFTSC --sequences AGCKNFFWKTFTSC AGCKNFFLKTFTSC

Signals

GitHub stars
242
Forks
42
Last commit
Aug 2026
Advanced
Catalog kind
skill
Gateway key
candidate-ranking
Source
github.com/lamm-mit/scienceclaw