cv-exam-sequence-padded-mask-loss

Overview

Variable-length CT series (one study has 200 slices, another has 800) cannot be batched directly — torch needs rectangular tensors. The standard fix is to pad to max_slices, but the trap is that any per-slice loss now includes the padded zeros and produces a meaningless gradient. Carrying a (B, max_slices) 0/1 mask and multiplying it into the per-element BCE before sum-and-divide is the fix. Crucially, normalize by the real slice count mask.sum(), not by max_slices — otherwise short studies produce artificially small losses and the optimizer ignores them. The same pattern applies to any padded-sequence regression (NLP token loss, point-cloud labeling, time-series anomaly per-step heads).

Quick Start

import torch
import torch.nn.functional as F

def padded_per_slice_bce(y_pred, y_true, mask, label_weight=1.0):
    """
    y_pred, y_true: (B, T) per-slice logits and targets
    mask:           (B, T) 1.0 for real slices, 0.0 for padding
    """
    raw = F.binary_cross_entropy_with_logits(y_pred, y_true, reduction='none')
    raw = raw * mask                                # zero out padding
    # per-exam normalization by real slice count
    n_real = mask.sum(dim=1).clamp(min=1.0)         # (B,)
    per_exam_loss = raw.sum(dim=1) / n_real          # (B,)
    # downweight short exams less aggressively with sqrt or log if needed
    return (label_weight * per_exam_loss).mean()

Workflow

1. In __getitem__, pad slice features to max_slices with zeros and produce a mask: mask[:n_real] = 1.0
2. Stack into batch tensors (B, max_slices, n_feats) and (B, max_slices) for the mask
3. In the loss, compute per-element BCE with reduction='none' then multiply by the mask
4. Sum over the time axis and divide by mask.sum(dim=1).clamp(min=1) to get per-exam loss
5. Mean over the batch (or sum if combining with other heads at exam level)
6. Apply the same masking inside any metric (AUROC, accuracy) — sklearn doesn't know about padding

Key Decisions

• reduction='none' then mask: never reduction='mean' followed by mask; the mean already divided by the wrong denominator.
• Normalize by mask.sum(), not max_slices: the latter underweights short exams by a factor of n_real / max_slices.
• clamp(min=1) on the divisor: defends against an empty exam in the batch (rare but possible with bad data).
• Mask is float, not bool: BCE multiplication needs float; bool works for simple slicing but not for the multiplication path.
• Apply the mask to the prediction before sigmoid in any per-slice metric: don't compute AUC over padded zeros, you'll get garbage.

References

• CNN-GRU Baseline - Stage 2 Train+Inference