reaction

SkillDev tools

For working with any terms in the catalytic activity branch; these often correspond to RHEA or EC terms

Available today. Use it from your connected AI after setup.

Connect ahel once, and every AI you use reads what you have installed.

Then ask your AI: use the reaction skill

What this skill tells your AI

The instructions your AI receives, as published by geneontology/go-ontology in .claude/skills/reaction/SKILL.md and read by ahel’s review.

Reaction terms may have mappings that are qualified using skos (using source qualifiers), as in the following:

[Term]
id: GO:0000140
name: acylglycerone-phosphate reductase (NADP+) activity
namespace: molecular_function
def: "Catalysis of the reaction: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP+ = 1-hexadecanoylglycerone 3-phosphate + H+ + NADPH." [RHEA:17341]
synonym: "1-acyldihydroxyacetone-phosphate reductase activity" EXACT []
synonym: "1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity" RELATED [EC:1.1.1.101]
synonym: "acyldihydroxyacetone phosphate reductase activity" RELATED [EC:1.1.1.101]
synonym: "palmitoyl dihydroxyacetone phosphate reductase activity" RELATED [EC:1.1.1.101]
synonym: "palmitoyl-dihydroxyacetone-phosphate reductase activity" RELATED [EC:1.1.1.101]
synonym: "palmitoyldihydroxyacetone-phosphate reductase activity" RELATED [EC:1.1.1.101]
xref: EC:1.1.1.101 {source="skos:exactMatch"}
xref: MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN {source="skos:exactMatch"}
xref: MetaCyc:RXN-15046 {source="skos:narrowMatch"}
xref: RHEA:17341 {source="skos:exactMatch"}
xref: RHEA:36175 {source="skos:narrowMatch"}
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28070" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28526" xsd:anyURI

Ideally there is a single source of truth for a reaction terms, which should be specified in the def xref

Signals

GitHub stars
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Last commit
Sep 2026
Advanced
Catalog kind
skill
Gateway key
reaction
Source
github.com/geneontology/go-ontology