sourmash Signature Compare Starter
SkillAI & modelsUse this skill to compute deterministic MinHash signatures for two tiny DNA sequences with sourmash and summarize their similarity in compact JSON.
Available today. Use it from your connected AI after setup.
No other account needed.
Connect ahel once, and every AI you use reads what you have installed.
Then ask your AI: use the sourmash Signature Compare Starter skill
About this capability
A framework for discovering, compiling, and validating reusable skills for scientific agents.
What this skill tells your AI
The instructions your AI receives, as published by ma-compbio-lab/skillfoundry in skills/genomics/sourmash-signature-compare-starter/SKILL.md and read by ahel’s review.
Use this skill to compute deterministic MinHash signatures for two tiny DNA sequences with sourmash and summarize their similarity in compact JSON.
What it does
- Reads two small FASTA inputs.
- Computes sourmash MinHash sketches with fixed
ksizeandscaled. - Reports hash counts, shared-hash count, Jaccard similarity, and pairwise containment.
When to use it
- You need a local, no-auth starter for metagenomics-style sketch comparison.
- You want a minimal example of sourmash sequence sketching without a large database.
- You want a deterministic JSON artifact for downstream tests or demos.
Example
slurm/envs/metagenomics/bin/python skills/genomics/sourmash-signature-compare-starter/scripts/run_sourmash_signature_compare.py \
--out scratch/metagenomics/sourmash_compare_summary.json
Verification
- Skill-local tests:
python3 -m unittest discover -s skills/genomics/sourmash-signature-compare-starter/tests -p 'test_*.py' - Expected summary:
shared_hash_count == 12andjaccard_similarity == 0.631579
Signals
- GitHub stars
- 39
- Forks
- 5
- Last commit
- Sep 2026
Advanced
- Catalog kind
- skill
- Gateway key
sourmash-signature-compare-starter- Source
- github.com/ma-compbio-lab/skillfoundry